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Ahmad R. Hariri

University of Pittsburgh

haririar@upmc.edu

Developmental Imaging Genetics Program
University of Pittsburgh
Pittsburgh, Pennsylvania 15213
United States
412-246-5879

Ahmad Hariri's Website
CV
NIH Biosketch
NSF Biosketch

Keywords:
emotion regulation, mood disorders, individual differences, genetics

Statement:
Since the mid-20th century, ever-increasing attention has been given to identifying specific biological pathways that contribute to complex cognitive and emotional behaviors, an endeavor paramount to our understanding of how individual differences in these behaviors emerge and how such differences may confer vulnerability to psychiatric disease. Recent advances in both molecular genetics and functional neuroimaging have begun to provide the tools necessary to explore these and other behaviorally relevant biological mechanisms. We have developed an experimental strategy by which genetic effects on brain function can be explored using multimodal neuroimaging techniques. In our program of research we use functional MRI and PET to explore the effects of genetically driven variation in neurotransmitter function on corticolimbic neural circuitry to delineate biological pathways and mechanisms by which individual differences in brain function emerge and potentially bias behavior and risk for psychiatric disorder.

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