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Lori Altshuler

300 UCLA Medical Plaza #1544

Los Angeles, California 90095
United States

Lori Altshuler's Website
UCLA Brain Research Institute
UCLA Psychiatry
NIH Biosketch
NSF Biosketch


Dr. Lori Altshuler is a Professor-in-Residence in the UCLA Department of Psychiatry and Biobehavioral Sciences and holds the Julia S. Gouw endowed chair in mood disorders. She is currently the Director of the Mood Disorders Research Program. The program conducts research involving patients with bipolar disorder and unipolar depressive disorder and has a strong neuroimaging component. Types of neuroimaging projects include:
  1. Cross-sectional structural studies evaluating limbic and frontal lobe volumes in patients with mood disorders in different mood states.
  2. Cross-sectional structural studies of euthymic subjects compared to controls.
  3. fMRI studies using tasks that probe response inhibition, affective regulation and working memory circuits in subjects with bipolar disorder and depression in episodes and in euthymia.
  4. Functional connectivity studies that assess changes in neural circuits (using tasks mentioned in #3 for the same subjects in different mood states).
  5. Studies involving the mapping of brain structure to function in patients with bipolar disorder.
  6. Neural predictors of treatment response in patients with bipolar II depression.
The program is additionally beginning to further explore DTI techniques. Investigators in the program work closely with collaborators Susan Bookheimer, Ph.D. and Paul Thompson, Ph.D. and their laboratories.

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