neuroscience, magnetic resonance, functional mri, fMRI, neurosurgery, brain mapping, cognitive neuroscience, eeg, positron emission tomography, ucla, neuroimaging, pulse sequences, alzheimer's, parkinsons, perception, neurophysiology, magnetic resonance imaging, functional magnetic resonance imaging, cognition, psychology, epilepsy, PET, optical intrinsic signal, OIS, QEEG, magnetoencephalography, MEG, spectroscopy

Principles of Neuroimaging A

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Catalog Course Description

Factors common to neuroimaging in multiple modalities including: Physiological Contrast mechanisms and Biophysics; Signal and Image processing, including transform approaches, Statistical Modeling and Inference, Time-Series Statistics, Detection Theory, Contrast Agents, Experimental Design, Modeling and Inference, Electrical Detection methods, Electroencephalography, Optical Methods, Microscopy.

Pre-Requisites

Functional Neuroanatomy (M292) and competence in 1) Integral calculus 2) Statistics 3) Electricity and Magnetism and 4) Computer Programming (any language). Waiver of some requirements may be possible by consent of the instructor.

Class Size

Class size is limited to 25 students, with priority given to students who are enrolled into the NeuroImaging Training Program

Textbooks

There is no core texbook for this course. Students will find the majority of the reading material on line and should prepare the readings prior to the in-class lecture.

Course Generalities [this link]

 

Syllabus (This is the start of the 2008 syllabus. Please note that I am still designing the syllabus based on the current class, thus mch of this is in DRAFT form)

LATE BREAKING NEWS: We will meet from now on in Room 58-261B on the Fifth Floor or NPI

Please note that many of the readings are password protected for copyright protection. If you are accessing this site for legitimate academic purposes, please contact Mark Cohen for password access.

Monday	Wednesday	Friday
1/7 Organizational - Cohen READINGS Andreasen NC. Brain imaging: Applications in psychiatry. Science. 1988;239:1381-8 Malhi GS, Lagopoulos J. Making sense of neuroimaging in psychiatry. Acta Psychiatr Scand. 2007 Nov 1 Poldrack RA. Can cognitive processes be inferred from neuroimaging data? Trends Cogn Sci. 2006 Feb;10(2):59-63. QUIZ and answers	1/9 The Image as a Hypothesis Test - Cohen If Neuroimaging is the Answer, What is the Question?	1/11 Neurons- Cohen READINGS The Active Brain SLIDES Assignment Due Monday 1/14: Two sentences: "What is an image?"
1/14 Neurons - Cohen READINGS The Active Brain SLIDES Further Reading: Neuroanatomy Programmed Learning Squire, et al.,: "Fundamentals Neuroscience" Kandel, et al., "Principles of Neural Science"	1/16 The Functional Organization of the Brain - Suthana Neuroanatomy is a requirement for this course. I strongly recommend that you take a look at the online course linked below. Today's lecture will cover a few organizing principles only. READINGS Levy, Malach. 2001 Dapretto, Bookheimer, 1999 SLIDES (link active as of 1/22/08) More Reading: Neuroanatomy Programmed Learning	1/18 Stats 101 - Cohen Further Reading: Statsoft online text Problem Set 1 - MATLAB practice
PROBLEM Set 11/21 MARTIN LUTHER KING HOLIDAY No Class	1/23 Stats 102 - Cohen Problem set 1 solutions In class MATLAB demo (linear correlation) READINGS Statsoft online text	1/25 N.B. Today's class starts at 2:30!!! Statistical Inference - Mumford READINGS Programmed text in Linear Algebra - Hefferon SLIDES for Mumford Talk printable version of above
1/28 Statistical Inference (2)- Mumford READINGS Programmed text in Linear Algebra - Hefferon SLIDES for Mumford Talk printable version of above Poole 2001	1/30 Linear Systems (intro) - Cohen READINGS Mathematical Tools	2/1
2/4	2/6 (Mark is away)	2/8
2/11 Electrical Circuits and LaPlace - Cohen READINGS Circuits Basics	2/13 Optical Intrinsic Signals - tbd	2/15 Dynamic Optical Spectroscopy - tbd
2/18 Washington's Birthday Holiday	Mark is Away	2/22 EEG circuit design - Cohen
2/25 Practical Implementation of EEG Circuits - Cohen	2/27 No Class - - Cohen	2/29
3/3 Oscillatory EEG and DEMO - Cohen Circuit used and results from our volunteer	3/5 EEG Signal Analysis - Soss READINGS Slides (password needed)	3/7 In lieu of a final, we had an in class discussion of these exam-like questions
3/10 TBD	3/12 EEG Signal Analysis II - Soss	3/14 Units and Oscillations - Ekstrom

For handouts indicated by * a $5 bounty is hereby offered for the first report of each factual error.